Semax 10mg
Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, extended with a Pro-Gly-Pro tail that confers resistance to enzymatic degradation. Supplied as 10mg lyophilized powder for in-vitro laboratory research.
About Semax
Semax was developed in Russia and carries the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro. The first four residues correspond to the 4-7 fragment of adrenocorticotropic hormone; the appended Pro-Gly-Pro tripeptide substantially slows enzymatic breakdown relative to the native ACTH fragment, which is the principal reason the analog is of interest to researchers.
Critically, Semax lacks the corticotropic activity of full-length ACTH. It does not stimulate cortisol release, which allows investigators to study the neuroactive properties of the ACTH(4-10) region in isolation from its endocrine effects.
Published research on Semax focuses on its interaction with brain-derived neurotrophic factor (BDNF) expression, modulation of the melanocortin system, and effects on monoaminergic signalling. It is classified as a nootropic research peptide and remains unapproved as a medicine outside the Russian Federation.
Specifications
| Compound | Semax 10mg |
| CAS number | 80714-61-0 |
| Classification | Synthetic ACTH(4-10) analog / nootropic peptide |
| Format | 10mg lyophilized powder, sealed vial |
| Purity | 99%+ verified by HPLC |
| Identity confirmation | Mass spectrometry |
| Certificate of analysis | Batch-specific, available on request |
| Storage | -20°C lyophilized · 2-8°C reconstituted |
| Shipping | Pan-India, dispatched within 24h of payment |
| Intended use | In-vitro laboratory research only |
Research applications
Semax is used in laboratory settings for work including:
- BDNF and neurotrophin expression studies
- Melanocortin receptor system investigation
- Peptide stability and enzymatic degradation profiling
- Comparative work against native ACTH(4-10) fragment
Handling and storage
Lyophilized Semax should be stored at -20°C for long-term stability and protected from light and moisture. The sealed vial tolerates ambient temperature for the duration of transit without meaningful degradation.
For reconstitution, bacteriostatic water is typically used. Add the solvent slowly against the inner wall of the vial rather than directly onto the powder, and allow the peptide to dissolve without shaking. Vortexing introduces shear forces that can damage peptide structure. Once reconstituted, store at 2-8°C.
Purity verification
Every batch Athenex Labs supplies is verified at 99%+ purity by high-performance liquid chromatography, with molecular identity confirmed by mass spectrometry. We source directly from ISO-certified manufacturers rather than through reseller chains, and we test independently rather than relying solely on supplier documentation. A batch-specific certificate of analysis is available on request.
Frequently asked questions
What is the purity of Athenex Labs Semax?
Every batch is verified at 99%+ purity by HPLC with mass spectrometry identity confirmation. A batch-specific certificate of analysis is available on request.
How should Semax be stored?
Store the sealed lyophilized vial at -20 degrees C for long-term stability, protected from light. Reconstituted solution should be kept at 2-8 degrees C. Semax in solution is less stable than in lyophilized form, so prepare working solutions close to the time of use.
What does Buy 4, Get 2 Free include?
Order four 10mg vials of Semax and two additional vials are added free, for six vials total. Mention the offer on WhatsApp at checkout.
Does Semax raise cortisol?
No. Although Semax is derived from an ACTH fragment, it does not retain corticotropic activity and does not stimulate cortisol release. This separation of neuroactive from endocrine properties is a central reason the analog is studied.
Research use only. Semax 10mg supplied by Athenex Labs is a research chemical intended exclusively for in-vitro laboratory investigation. It is not a drug, supplement or medicine. It is not for human or animal consumption and is not intended to diagnose, treat, cure or prevent any disease. By purchasing you confirm that you are a qualified researcher or represent a research institution, and that the material will be used solely for legitimate scientific research.